Furthermore, chaperonins protect tumor cells from stress, allowing them to survive and proliferate [21], and the bioinformatics analysis revealed HSPD1 (the molecular chaperone or chaperonin type I Hsp60) and CCT5 subunit (a component of the type II CCT chaperonin) among the target genes of the miRNAs examined. Here, HSPD1 is linked to neoplasm.