BRCA1 and Familial prostate cancer: Robinson et al. have identified mutations in three DNA repair genes, BRCA1, BRCA2, and ATM, in men unselected for age at diagnosis or family history, but rather for aggressive disease [7], and the 19.3% of prostate cancers and 23% of prostatic cancer castration-resistant patients had BRCA1, BRCA2 or ATM mutations [7,13].