TNFSF13B and peeling skin syndrome: In another study, while anti-Ro/SSA and anti-La/SSB were present in all pSS patients, three distinctive molecular phenotypes were identified: (1) no significant elevation of IFN or inflammation modules; (2) strong IFN and inflammation modular network signatures and high plasma protein levels of CXC Motif Chemokine Ligand 9 and 10 (CXCL9/10), BAFF and tumour necrosis factor superfamily member 14 (TNFSF14 or LIGHT); and 3) moderately elevated IFN modules, suppressed inflammatory modules, and increased plasma levels of CXCL9/10/13, IL-1a, and IL-21 [39].