Our findings revealed that a total of 12 PSMs exhibited higher expression in AML compared to MNCs, specifically PSMA1, PSMA2, PSMA4, PSMA5, PSMA7, PSMB1, PSMD2, PSMD3, PSMD4, PSMD8, PSMD13, and PSMG2. This evidence concerns the gene PSMA2 and acute myeloid leukemia.