Additionally, FCH-enriched serum induced the upregulation of other proteins involved in the immune response that have been described for their beneficial roles in skin pathologies such as atopic dermatitis (AD) and psoriasis (e.g., zinc-alpha-2-glycoprotein (AZGP1, ZAG), guanylate-binding protein 2 (GBP2) and N-acetylmuramoyl-L-alanine amidase (PGLYRP2)). Here, GBP2 is linked to Alzheimer disease.