For example, a recent meticulous study demonstrated that MIR-27a-5p, which is involved in sepsis progression (more specifically, sepsis-induced lung injury), could act in inhibiting GSDMD mRNA, which promotes pro-inflammatory response by enhancing cytokine release and pyroptosis, and on the other hand, this miR is sponged out by LNC-ZNF33B-2.1, which regulates its activity [41]. Here, GSDMD is linked to Sepsis.