Glucagon-like peptide-1 receptor agonists, dual glucagon-like peptide-1 and gastric inhibitory polypeptide agonists, sodium-glucose cotransporter-2 inhibitors, metformin, pramlintide, and some other drugs are discussed as promising therapeutic agents for the management of obesity and/or insulin resistance in patients with T1D [49,50]. The gene discussed is SLC5A2; the disease is obesity due to melanocortin 4 receptor deficiency.