SIGLEC8 and asthma: This study found a weak but statistically significant correlation between the proportion of CD62Llow eosinophils (“iEos”, percent of total isolated Siglec8+CD16− eosinophils) and asthma control parameters, as assessed by the Asthma Control Test (ACT), the Asthma Control Questionnaire-5 (ACQ-5), and history of asthma exacerbations [43].