Univariate logistic regression analysis revealed that the following were all associated with CAD: a decrease in platelet adhesion after GPIb inhibition; VWF:CB activity; smoking; HDL cholesterol values of <1.0 mmol/L for males and <1.2 mmol/L for females; diabetes mellitus; and male sex (Table 5). The gene discussed is VWF; the disease is diabetes mellitus.