SHPRH and hepatocellular carcinoma: Moreover, various circRNA-encoded proteins and peptides—such as circFBXW7, circFNDC3B, circLgr4, circPPP1R12A, circMAPK1, circβ-catenin, circGprc5a, circ-SHPRH, circPINTexon2, and circAKT3—have been linked to human malignancies, including GC, hepatocellular carcinoma (HCC), bladder cancer, triple-negative breast cancer, colon cancer, and glioblastoma.