SPARC and cancer: Among the 115 CAFGs identified in CRC (CRC CAFGs), 59 genes (64%) were also closely associated in expression with SPARC in cancer stroma of BC (R = 0.6 or beyond) from the 92 genes on the microarray chips, whereas their SE ratios were barely beyond 10 (average = 3.8, Table S1 and Figure 1a).