Recent molecular classification by single-cell transcriptomic analysis (scRNA technology) of an animal BC model clarified that CAFs were composed of vascular CAFs (vCAFs), matrix CAFs (mCAFs), cycling CAFs (cCAFs), and development CAFs (dCAFs) [10], of which the predominant group, vCAFs (~70%), may affect angiogenesis, while the second most abundant group, mCAFs (~20%), secrete extracellular matrix (ECM) materials such as FBLN1, DCN, LUM, and FBLN2, which were accompanied by CDH1, PDGFRA, and LRRC15. This evidence concerns the gene LRRC15 and breast cancer.