The L-CAFGs according to expression amounts are shown in Figure S1b, ranked as top of the L-CAFGs in BC like ATF4, followed by ITGAV, TGFBR2, NOTCH2, TIMP1, CRELD2, HIF1A, MAPK14 (p38), SMAD2, ROCK1, ADAM10, NOTCH1, MAPK1 (ERK2), IGF1, MRC2, NFKB2, AKT1, AKT3, and IGF1R. This evidence concerns the gene CRELD2 and breast cancer.