Zhou et al. also added the thrombin–antithrombin III complex (TAT), the plasmin-α2–plasmininhibitor complex (PIC), thrombomodulin (TM), and the tissue plasminogen activator–inhibitor complex (t-PAIC), which play crucial roles in the venous thrombosis process and can be elevated before thrombus formation, as good PE biomarkers [67]. This evidence concerns the gene THBD and Venous thrombosis.