APOE and Alzheimer disease: The results show a significant association among APOE ε2 (OR = 0.47, 95% CI [0.29–0.74], p = 0.0013), APOE ε3 alleles, and AD (OR  =  0.49, 95% CI [0.37–0.65], p < 0.0001), highlighting the lower risk of AD for the ε2 and ε3 alleles.