A more comprehensive analysis indicates that upregulated proteins (ELOVL5, ELOVL7, TECR, HSD17B4, ACSL1, HACD2, and CBR4) are significantly enriched within the pathways of oxidative phosphorylation and metabolic pathways pertinent to amyotrophic lateral sclerosis. This evidence concerns the gene ELOVL5 and amyotrophic lateral sclerosis.