A more comprehensive analysis indicates that upregulated proteins (ELOVL5, ELOVL7, TECR, HSD17B4, ACSL1, HACD2, and CBR4) are significantly enriched within the pathways of oxidative phosphorylation and metabolic pathways pertinent to amyotrophic lateral sclerosis. Here, HACD2 is linked to amyotrophic lateral sclerosis.