Recently, Pu and collaborators demonstrated that elevated monoamine oxidase B (MAOB) in stromal fibroblasts contributes to PCa progression by promoting a reactive stroma, through enhanced ROS production and increased levels of stromal markers (i.e., TGF-B1, VIM and FAP), and favoring the interaction between stromal and epithelial cells via CXCL12/CXCR4 signaling activation [140]. This evidence concerns the gene MAOB and posterior cortical atrophy.