A study by Fang et al. [61] found that EGCG decreased the activity of MMP-2 and MMP-9 in Epstein–Barr virus-negative and -positive nasopharyngeal carcinoma (NPC) cell lines in a concentration-dependent manner, probably by modulating the ERK and NF-κB pathways. This evidence concerns the gene NFKB1 and nasopharyngeal carcinoma.