In a study by Zhao and co-workers [33] on the hepatocellular carcinoma cell lines HepG2 and SK-Hep-1, Western blot analysis showed a significant reduction in MMP-2 and MMP-9 expression, resulting in strong anti-proliferative, anti-metastatic, and anti-invasive effects. The gene discussed is MMP2; the disease is hepatocellular carcinoma.