Our analyses of publicly available microarray data using the (KM Plotter) tool for breast cancer showed that high levels of expression of KIFC1 (Figure 2E), AURKB (Figure 2F), BIRC5 (Figure 2G), and CDCA8 (Figure 2H) predicted significantly poorer recurrence-free survival of breast cancer patients, suggesting that upregulation of centrosome clustering mechanisms could potentially contribute to disease progression in breast cancer patients. The gene discussed is BIRC5; the disease is breast cancer.