CD8A and colorectal carcinoma: Representative staining of CD8+ TILs/HPF for FAP and collagen marker-high and low CRC tissues are shown in Figure 5A. The statistical significance between the average number of CD8+ TILs/HPF for each CAF marker compared to the average number of CD8+ TILs/HPF in each respective marker-absent tissue sample was assessed with Mann–Whitney analyses (Figure 5B).