Both infiltrating-type primary CRC lesions and rHPG CRCLM were associated with mutations in APC (3⁄5) and TP53 (3⁄5), KRAS, FAT4, DNH5, SMAD, ERBB2, ERBB3, LRP1, and SDK1 (1⁄5). This evidence concerns the gene TP53 and colorectal carcinoma.