CMTM6 and brain glioma: Additionally, in an analysis of tumor biopsies, it was reported that CMTM6 gene expression was upregulated in numerous tumors, such as colon adenocarcinoma, glioblastoma multiforme, acute myeloid leukemia, lower-grade brain glioma, ovarian serous cystadenocarcinoma, pancreatic, rectal and stomach adenocarcinomas, thyroid carcinoma, and uterine corpus endometrial carcinoma.