HMOX1 and rheumatoid arthritis: It promotes chondrocyte recovery and exhibits anti-inflammatory and antioxidant effects through the nuclear factor kappa B (NF-kB) and nuclear factor erythroid 2-related factor (Nrf2) transcription factor/Hemoxygenase 1 (HO-1(Nrf2/HO-1) pathways, suggesting its therapeutic promise for RA [101].