The mechanisms by which WFA exerts its anti-cancer effects include the inactivation of Akt and NF-κB [27,28], the generation of ROS [29], cell cycle arrest in the G2/M phase [30], the induction of caspases and other pro-apoptotic proteins [31], and the inhibition of key survival proteins such as HSP90, Notch-1, and HPV oncoproteins E6 and E7 [18]. The gene discussed is NFKB1; the disease is cancer.