Modulators of AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α), dynamin-related guanosine triphosphatase (Drp1), and a number of other proteins that can regulate mitochondrial morphology and function have a protective effect against diabetes and its related complications [4,9,10,11]. This evidence concerns the gene PPARGC1A and diabetes mellitus.