TP53 and neoplasm: Based on the KEGG-enriched pathway analyses, several pathways were involved in the invasion and migration of tumor cells after the treatment with curcumol compared to the control group, such as ubiquitin-mediated proteolysis, TGF-β, PI3K-Akt, p53, mTOR, MAPK, Hippo, and HIF-1 signaling pathway, focal adhesion, cell cycle, animal autophagy, and apoptosis (Figure 1D).