NUCLEOLIN and nasopharyngeal carcinoma: Especially given we know curcumol has a good activity of NPC, based on using the transcriptomics analysis study out the differentially expressed genes (DEGs), differentially expressed proteins (DEPs) were carried out by the proteomics analysis with knockdown of the key proteins of NCL and EBNA1, respectively, and metabolomics analysis of the correlation of differential metabolites with key proteins.