CCL2 is a secreted factor expressed during normal immune surveillance, as well as in response to injury or infection. It influences a variety of tumors and diseases, including atherosclerosis, multiple sclerosis, and diabetes. Furthermore, CCL2 plays a critical role in the immune system by attracting immune cells to adipose tissue through chemotaxis, which is vital for macrophage infiltration into adipose tissue. This evidence concerns the gene CCL2 and multiple sclerosis.