Interesting, cBDNF(1-12) and cNT3(1-13) are able to mimic these features of their related proteins and induce the expression of Trks and VEGFRs (Figure 5); to the best of our knowledge it is the first time that NT mimetics have shown these abilities that can promote neurogenesis and angiogenesis in AD. This evidence concerns the gene SLC28A3 and Alzheimer disease.