Network pharmacology analysis revealed that emodin is involved in the apoptosis signaling pathway and that the main targets of emodin are apoptotic proteins such as BAX, Bcl-2, and caspase 3; compared with the AP model, treatment with emodin can restore the expression of intestinal mucosal-barrier-related proteins and inhibit the expression of the proapoptotic proteins BAX and caspase 3, thereby protecting against intestinal mucosal barrier damage and inhibiting the apoptosis of intestinal epithelial cells [125]. The gene discussed is BAX; the disease is alkaline phosphatase measurement.