TNF and pulmonary embolism: ✓LMWH administration significantly improved the levels of blood and urine amylase, the CT score (p < 0.05–0.01), and reduced pulmonary embolism occurrence rate, mortality, and mean hospital stay (p < 0.05–0.01) [116]. ✓LMWH results in reduced index progressed in (8.6 vs. 31.4%), and necrosis (5.71 vs. 25.71%) [112].✓LWMHs combined with ulinastatin showed a shorter time to return to normal (p < 0.05). The levels of IL-10 in LWMH group were higher, while sB7-H2, TNF-α, sTREM-1 and IL-1 levels were lower than those (p < 0.05) [115].