Similarly, decorin underglycanation has been detected in the skin and bone of a mouse model of gerodermia osteodysplastica (MIM 231070) caused by defects in the GORAB gene encoding for a component of the COPI-coated vesicles responsible for retrograde transport from the Golgi apparatus to the ER and trafficking between cisternae within the Golgi apparatus [38,39]. The gene discussed is DCN; the disease is geroderma osteodysplastica.