TGFA and chronic kidney disease: To determine whether NHERF1-dependent decrease in miRNA-153 and an increase in nuclear expression of NFATc2 and NFATc3 will increase expression of known proinflammatory cytokines involved in chronic kidney disease, viz., IL-1, IL-6, IL-17, MCP-1, and TGFα, we measured the expression of cytokines in the kidney homogenates by ELISA.