The study demonstrated the association of these anti-TIF1-γ-associated antibodies with Raynaud’s phenomenon and less severe muscle disease, and anti-CCAR1 autoantibodies with panniculitis, which suggests that the heterogeneity of anti-TIF1-γ positive JDM is attributed to the presence or absence of these autoantibodies [68]. Here, TRIM33 is linked to juvenile dermatomyositis.