To elucidate whether ALMS1‐IT1 modulates ferroptosis activity in CRC by promoting STAT3 phosphorylation, we conducted experiments using cell models overexpressing ALMS1‐IT1 and treated them with a combination of ALMS1‐IT1 overexpression and stattic, a STAT3 inhibitor. The gene discussed is ALMS1; the disease is colorectal carcinoma.