The fact that in the present study, oHSV-1 treatment also results in an increased recrutitment of FOXP3 + cells suggests that these cells are not associated with an inhibitory function toward the anti-tumor response or that they were inhibited in their suppressive function by a mechanism that remains unclear, but is certainly related to the immune response triggered by the oncolytic virus. Here, FOXP3 is linked to neoplasm.