Similarly, RANTES or CCL5 are released by α-granules and are binding to endothelial cells to enhance atherogenic T lymphocyte recruitment [156, 157].The α-granular contents release during platelet activation at sites of vessel wall injury and thus play an important role in hemostasis, inflammation, wound repair, and the pathogenesis of atherosclerosis and similar vascular conditions [158]. This evidence concerns the gene CCL5 and atherosclerosis.