The MAN1C1High samples exhibited an increase in the release of cancer cell antigens (Step 1) and the trafficking of immune cells, including T cells, CD4 + T cells, CD8 + T cells, Th1 cells, DCs, Th22 cells, MO, monocytes, neutrophils, NK cells, basophils, Tregs, and MDSCs, to tumors (Step 4). Here, CD8A is linked to cancer.