Additionally, as seen for N999Vfs*40 KIF5A, no co-distribution was observed between mitochondria and C975Vfs*73 KIF5A aggregates (Fig. 7C), hinting at a shared loss of function between ALS- and NEIMY-KIF5A mutants that would be consistent with reports implicating mitochondrial dysfunction in both phenotypes [13, 14, 26]. The gene discussed is KIF5A; the disease is amyotrophic lateral sclerosis.