TRPV4 and Charcot-Marie-Tooth disease axonal type 2C: We explore the molecular mechanisms through which TRPV4 contributes to disease pathogenesis in conditions such as inflammation, neuropathic diseases (e.g., Alzheimer’s, Charcot- Marie-Tooth disease type 2C), and specific cellular and molecular pathways involving TRPV4, providing insights into its multifaceted involvement in these disorders.