Furthermore, in contrast to the CHB group, the HBV-ACLF group exhibited higher expressions of the inflammatory cytokines linked to liver failure, such as IFN-γ and IL-6, with trends resembling those of Gal-9, indicating that Gal-9 may be a biological marker for HBV-ACLF. The gene discussed is LGALS9; the disease is Hepatic failure.