These included 2 subjects with multiple sclerosis, 1 subject with systemic lupus erythematosus, 1 subject with diploid-triploid mosaicism, 1 subject with mosaic KRAS-related RASopathy, and 1 subject with Myoclonic epilepsy with ragged-red fibers (MERRF) (Table 1). This evidence concerns the gene KRAS and RASopathy.