SYNJ1 and Parkinson disease: The monogenic form of parkinsonism (OMIM phenotypic series 168600) is genetically and clinically heterogeneous, including several rare early-onset cases due to recessive mutations in the genes SH3GL2, SYNJ1, and DNAJC6, which encode proteins with critical synaptic functions such as Endophilin A1, Synaptojanin 1 and Auxilin, respectively.10