CDH4 is incorporated in the molecular prognostic scoring system for predicting OS in ccRCC by Peng et al The system consisted of 21 DEGs including CDH4, DDAH1, CRABP2, TGFA, SEMA3G, SPATA18, PTTG1, SCGN, CYP39A1, CLDN4, ZNF395, IL15RA, APLNR, APOLD1, NTN4, PABPC1L, UBE2C, GNG7, CEACAM1, PLAUR, and SIM2. Here, SIM2 is linked to nonpapillary renal cell carcinoma.