Also, it was positively correlated with tumor stage, lymph node metastasis, and histopathological grade of RCC patients.[49] Additionally, a prior study reported that increased SAA1 levels are linked to poorer prognosis and an increased likelihood of distant metastasis in patients with pRCC.[50] Based on these findings, it is well established that SAA1 exerts an oncogenic role, suggesting its potential in promoting cancer growth and developing metastasis. The gene discussed is SAA1; the disease is renal cell carcinoma.