GH1 and pituitary gland adenoma: This hormonal imbalance causes numerous systemic complications, encompassing cardiovascular, respiratory, metabolic, musculoskeletal, neurological, and neoplastic issues.[1] The initial clinical case of acromegaly was documented in 1567, with the term “acromegaly” being coined by French neurologist Pierre Marie in 1886.[2] About 99% of acromegaly cases stem from GH-secreting pituitary adenomas.