These genes have emerged as significant genes in prior studies on serum omega‐3 fatty acid,[39] a crucial type of polyunsaturated fatty acids that have demonstrated favorable impacts on age‐related diseases (e.g., CVD and metabolic diseases).[40] We also identified several genome‐wide significant genes on chromosome 16, such as TXNL4B, HPR, and HP. The gene discussed is TXNL4B; the disease is metabolic disease.