It has been hypothesised that the same oxidative metabolites responsible for methaemoglobinaemia are also responsible for inducing haemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficiency, killing mature gametocytes of P. falciparum, and killing liver stage hypnozoites [8]. Here, G6PD is linked to hyperinsulinemic hypoglycemia, familial, 4.