The rationale is related to the peritoneal fluid of endometriosis-afflicted patients has been discovered to include high concentrations of angiogenic factors and inflammatory cytokines, such as IL-1β, IL-6, and IL-10, inducing the synthesis of VEGF (vascular endothelial growth factor) and MCP-1 (monocyte chemotactic protein) by macrophages [4–6]. The gene discussed is VEGFA; the disease is endometriosis.