CXCR4 and colorectal carcinoma: Specific objectives of the presented work were (1) the establishment of a CAM-PDX model based on PDOs derived from a liver metastasis of a CRC patient and (2) the evaluation of the presented translational pipeline (patient – in vitro PDOs – in vivo CAM-PDX) regarding morphology, histopathology, expression of CXCR4, and radiotracer uptake patterns.