The results of different expression patterns of RENT3B in pan-cancer are shown in Fig. 1B. High expression of RENT3B was observed in BRCA (Breast invasive carcinoma), CHOL (Cholangiocarcinoma), BLCA (Bladder Urothelial Carcinoma), ESCA (Esophageal carcinoma), COAD (Colon adenocarcinoma), HNSC (Head and Neck squamous cell carcinoma), HNSC-HPV positive (Head and Neck Squamous Carcinoma-HPV positive), LIHC, LUAD (Lung adenocarcinoma), STAD (Stomach adenocarcinoma), READ (Rectum adenocarcinoma), LUSC, and UCEC (Uterine Corpus Endometrial Carcinoma). The gene discussed is UPF3B; the disease is rectum adenocarcinoma.