Overall, RENT3B was found to be an indicator of poor prognosis in most cancers (RENT3B, OS: n = 9493, HR = 1.3, log-rank p = 4.6e-10; DFS: n = 9502, HR = 1.2, log-rank p = 2.2e-05) (Fig. 3A, B). The gene discussed is UPF3B; the disease is cancer.