VPS13B and Cohen syndrome: In agreement with localization of VPS13B in the Golgi complex (Seifert et al., 2011, 2015), a less compact Golgi structure and an altered N-glycosylation pattern were observed in cells from Cohen syndrome patients and in several mammalian VPS13B knock-out (KO) and knock-down cell lines (Seifert et al., 2011; Duplomb et al., 2014; Zorn et al., 2022).