In line with the serum data, the expression of pro-inflammatory cytokine genes (CXCL1, IL-17A, and iNOS) was also reduced in the colonic tissues of CAPE-treated ETBF/AOM/DSS mice compared to the control ETBF/AOM/DSS mice (Figure 4D–F). This evidence concerns the gene CXCL1 and infectious otitis media.