Binding of HRP-MBP-Atl1 indicating the presence of O6-AlkG adducts in five tumour DNA samples (mean ± SD 1.24 ± 0.25; range 0.98–1.53 O6-meG equivalents/μg DNA) with trace levels detected in one other sample (Figure 5). The gene discussed is ATL1; the disease is neoplasm.